Some inline comments can be quite in-depth if they raise a design issue. (My team is not based in the same location, so these discussions don't always arise face-to-face, but are hashed out in Differential, which we use somewhat as a "Request for Comments" mechanism as well as a review tool.) As such, we often want to quote part of a lengthy inline comment in a reply. At the moment this is tedious. We have to use copy/paste, which doesn't preserve any of the Remarkup. What's worse, you can only copy/paste from where the inline comment appears in the transaction on the timeline, not where it appears within the code/diff (for some reason, text selection simply doesn't work there, at least using my FF Mac browser).
A quote facility for inline comments would solve this. Perhaps a quotation mark icon beside the reply icon which opens a reply prefilled with the quoted inline comment.
A somewhat-related issue is the ability to edit inline comments. From time to time I have wanted to do this.
Perhaps the most commonly used actions (reply, previous, next) could live in the comment header, but less frequent ones move to a menu like comments on the timeline (quote, edit, hide, view raw?).