My general workflow when reviewing code is (1) request changes with inline comments, (2) wait for new revision, (3) load incremental diff view with inline comments, (4) examine the changes made in response to each comment.
This breaks down when a new file gets renamed between revisions because Differential considers the two files to be fully independent. Incremental diff view is not able to show me any of the changes between the two versions. Using an external diff tool is a poor substitute because it doesn't allow me to see my inline comments next to the changes.
It would be awesome if Differential could detect this case and show a normal incremental diff.